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Aging and Circadian Rhythm: Do Changes in Our Biological Clock Affect Health?

Aging is an inevitable process that affects every aspect of our body and health. As we age, our body undergoes changes in various physiological functions, including the circadian rhythm – also known as the biological clock. The circadian rhythm is responsible for regulating several essential bodily functions such as sleep-wake cycles, body temperature, and hormone production. Any disruption in the circadian rhythm can result in various health problems, affecting our overall health and well-being.

Age-related changes in the circadian rhythm:

The circadian rhythm is controlled by the hypothalamus, which receives light signals from the eyes to synchronize the body’s clock to the external environment. However, as we age, the hypothalamus becomes less sensitive to light signals, causing a misalignment between the body’s internal clock and the external world. This results in several age-related changes in the circadian rhythm, such as:

1. Changes in sleep-wake cycle: As we age, our sleep patterns change, and we tend to sleep less and have more fragmented sleep. This is due to a decrease in the secretion of the sleep-inducing hormone melatonin, which is controlled by the circadian rhythm.

2. Changes in body temperature: The circadian rhythm controls the body’s core temperature, which tends to decrease as we age. This is why older adults tend to feel cold more often.

3. Changes in hormone production: The circadian rhythm controls the production of several hormones such as cortisol, growth hormone, and testosterone. As we age, the production of these hormones decreases, affecting various bodily functions.

Impact of circadian rhythm on health:

Disruptions in the circadian rhythm can have several health consequences, including:

1. Alzheimer’s disease: Studies have shown that a disrupted circadian rhythm is associated with the development of Alzheimer’s disease. This is because the brain’s waste removal process, which occurs during sleep, is affected when the circadian rhythm is disrupted.

2. Cardiovascular diseases: Disruptions in the circadian rhythm have been linked to the development of several cardiovascular diseases, including high blood pressure, heart attack, and stroke.

3. Metabolic disorders: The circadian rhythm plays a vital role in regulating glucose metabolism and insulin sensitivity, and any disruption in this rhythm can lead to the development of metabolic disorders such as diabetes, obesity, and metabolic syndrome.


The circadian rhythm plays a critical role in regulating various bodily functions, and any disruption in this rhythm can have serious health consequences. As we age, our circadian rhythm undergoes changes, leading to sleep problems, hormonal imbalances, and other health issues. Therefore, it is essential to maintain a healthy circadian rhythm by maintaining good sleep hygiene, getting enough exposure to natural light, and following a healthy lifestyle. By maintaining a healthy circadian rhythm, we can promote healthy aging and reduce the risk of developing age-related diseases.


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